Information on Heroin Use leading to AddictionHeroin is an opiate (prepared from morphine by chemical treatment) with biochemical effects related to emotional and physical pain relief. Opiates like heroin bind to painkilling sites throughout the brain, known as opioid-Mu receptors or the "reward pathway." This leads to slower uptake of neurotransmitters, like dopamine, between neurons. Immediate effects include cessation of pain, drowsiness, and a feeling of well-being associated with pain reduction.With chronic use of heroin, the brain may stop producing endorphins, natural painkilling chemicals, because it has gotten used to heroin, that is, the brain shows a change in its circuitry, and only functions normally in the presence of heroin. The user must replace the missing endorphins with heroin in order to feel well. But because the brain has adapted to heroin, it becomes less sensitive to it, so the dosage will have to be increased gradually to obtain the original effects of heroin. This is called tolerance, which usually leads to dependence/addiction. Dependence/addiction occurs when a
constant supply of the opiate is supplied. When this drug is withdrawn several
physiological reactions occur. When the heroin is taken away, neurons
that have long been inhibited, start pumping out neurotransmitters again.
This imbalance of chemicals in the brain interacts with the nervous system
to produce the classic opiate withdrawal symptoms: nausea, muscle spasms,
cramps, anxiety, fever, diarrhea. These symptoms can be very serious and
the abuser will use the drug again to avoid the withdrawal
syndrome.
The physical effects of heroin use and Symptoms of addiction to heroinThere are some symptoms that indicate
dependence/addiction on heroin: What are effects of heroin addiction?Heroin damages the nervous
system and can also cause short and long term harm to the respiratory and
cardiovascular systems. On the other hand, heroin
dependents decrease their ability to function both mentally and physically. The
physical effects of heroin dependence/addiction may include:
Heroin Detox Center (Opiates):� TAVAD
- Advanced Addiction Treatments
For further information about Opiates and Heroin Addiction:Frontline. Heroin in the brain. Its
Chemistry and effects. |